I Heard the People Sing at Les Miserables!

I adore musicals. Tech Support is more skeptical of the genre, despite having a deep love of Fiddler on the Roof and Paint Your Wagon. But since he’s a good husband, he took me to Les Mis for Valentine’s Day. I’d seen it live a couple of times before, but this was the fancy new touring production. Not sure I’m on board with it. They took out the “time and place” signals, which made it tough…

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Intent to Kill and the Forensics of Hang Fire

There has been a ton of debate online in the wake of the latest shootings in the States. One thing no one argues about is whether or not the shooters intended to commit murder, because of course they did. Canadians, on the other hand, have been debating the question of intent – in the Gerald Stanley/Colten Boushie case. Did Stanley shoot to kill, or did his gun experience a rare malfunction? Called hang fire, it…

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Who’s Your Favourite Fantasy Author?

Confession: I’ve been hoarding Terry Pratchett novels ever since he first announced he had Alzheimer’s disease. I’ve been doling them out to myself as rare and hard-to-earn rewards because I knew there would come a day that he wouldn’t be able to write any more. And on that day, I would lose forever the joy of reading one of his works for the very first time. I read Snuff as my treat for finishing the…

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Why Tech Support is Cranky

Tech Support is cranky. When we decided to move to Ontario, our primary concerns were: Being close enough to Toronto to get there if we wanted, but far enough away that the hordes of people wouldn’t make me too ragey Being close enough to Toronto to get there when we needed, while still being able to afford a house.   When we researched the town we now live in, we thought we’d lucked out. Everyone…

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Great Big Book News!

*emerges from hiding* *checks to see whether anyone is still here* *pulls out bullhorn and confetti cannon* I’M WRITING A BOOK FOR KIDS CAN PRESS. KIDS CAN PRESS, PEOPLE.   Unless you’re in the biz, you may not know that Kids Can Press was named Best Children’s Publisher in North America for 2017. You might not know that Kids Can Press publishes beautiful, wonderful, ground-breaking books by some seriously awesome Canadian authors and illustrators, including…

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Gene Therapy: Embryonic Engineering and the Future of Human Evolution

Welcome to Part 3 of my series on gene therapy and genetic engineering. If you haven’t already, I’d suggest reading Parts 1 and 2 before you continue: Introduction to Gene Therapy: It Sounds Simple, But It’s Sure Not Easy Gene Therapy: Vectors, Viruses, and Why CRISPR Will Change Everything Today, we’re talking about the second major challenge with gene therapy – getting replacement DNA into EVERY affected cell in a patient’s body – and why…

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Gene Therapy: Vectors, Viruses, and Why CRISPR Will Change Everything

Welcome to Part 2 of my series on gene therapy! If you haven’t already, I recommend that you read Part 1, Introduction to Gene Therapy: It Sounds Simple, But It’s Sure Not Easy, before continuing with this post. Ready? Here we go. Viruses: FedEx For Genes Gene therapy involves repairing or replacing a faulty gene that has led to disease. In order to do that, one major hurdle must be overcome: getting new DNA into…

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Thoughts on Finishing Season 12 of Supernatural on Netflix

NOOOOOOOOOOOO!   HOW CAN YOU KILL THAT MANY KEY CHARACTERS IN A SINGLE EPISODE ARE YOU KIDDING ME WITH THIS THERE HAD BETTER BE SOME SERIOUS RESURRECTIONS COMING IN THE PREMIER OF SEASON 13 OR THERE WILL BE RAAAAAAAAGE!!! Am I overreacting here? The post Thoughts on Finishing Season 12 of Supernatural on Netflix appeared first on L. E. Carmichael.

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Introduction to Gene Therapy: It Sounds Simple, But It’s Sure Not Easy

Muscular dystrophy, hemophilia, Leber congenital amaurosis (LCA), cancer… they all have one thing in common. They are genetic diseases, ultimately caused by missing or malfunctioning genes in the patient’s DNA. Until recently, we could treat the symptoms of many genetic diseases, but not the causes. There was no way to reach inside a person’s genes and repair the faulty code that started the whole problem. Research into gene therapy aims to change that. What is…

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New Province, New Adventures

So I live in Ontario now. It’s not a whole lot different yet, probably because I spend 90% of my time in the house and when I leave, it’s for Home Depot or groceries. Because new houses need curtain rods and shelving, and, well, there is only so long a person with food allergies can survive on even the most well-researched take out. Last weekend, though, Tech Support and I decided it was time to…

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