A new kind of problem
The PhD student and I are analyzing the data from his mapping of H. influenzae's uptake of genomic DNA. The data was generated by Illumina sequencing of genomic DNA samples before and after they had been taken up by competent cells. Using a rec2 mutant as the competent cells lets us recover the DNA intact after uptake.He has done quite a bit of analysis of the resulting uptake ratios (ratio of 'recovered' coverage to 'input'…
