Credit: Creative Commons The convergence of tissue engineering, regenerative medicine (TERM) and artificial intelligence (AI) has ushered in a transformative era for the biomedical field. By leveraging machine learning (ML) and deep learning (DL), researchers can enhance cell culture processes and advance organ and tissue engineering. Specifically, DL accelerates the development of regenerative therapies by...

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Credit: Jason D. Williams, CCO, Wikimedia Commons If you’re reading this, you’re probably aware of the massive strides the cell and gene therapy (CGT) industry has made in the last few years. Between 2017 and 2022, six CGT products were approved by the U.S. Food and Drug Administration, but we saw eight approvals in 2023...

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Gartner Hype Cycle diagram. Creative Commons. Are you familiar with the Gartner Hype Cycle? It’s a way of separating hype from reality when it comes to emerging technologies – like cell and gene therapies (CGTs). The hype cycle employs a graph to present the maturity of new technologies through five phases. Learn more here. The...

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A photo of Marcella Townsend following treatment for severe facial burns using placenta-derived grafts. Credit: Kendrick Brinson/The New York Times/Redux Millions of placentas are discarded annually around the world. Given the regenerative medical potential demonstrated by placenta-derived tissue over the years, this is quite an unfortunate statistic. First used in 1910, placenta-derived tissue was abandoned...

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Parmin Sedigh is an undergraduate student who is passionate about the stem cell field and science communication. You can find her on LinkedIn and @ParminSedigh, or view her portfolio website. Three years ago, I wrote a blog post for Signals on why I’m passionate about stem cells and science communication as a high school student, and...

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As a member of CCRM’s Communications team, I am always keen to learn about the different ways that communication can bridge the knowledge gap between various stakeholders and complex scientific work and discoveries in regenerative medicine. Known as scientific communication (scicomm), this field provides rewarding careers for people with life sciences degrees. The Careers Beyond...

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L-R Drs. Isebelle Riviere and Michel Sadelain at screening of Living Drugs in Toronto, part of Gairdner Science Week 2024 Michel Sadelain is the 2024 Gairdner International Award laureate, along with Dr. Zelig Eshhar, for his “seminal contributions to the conception, development and application of CD19-CAR T cell therapy for cancer.” It’s been a good...

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CCRM, the publisher of Signals, has enhanced its long-standing relationship with the University of Toronto’s Medicine by Design through a new strategic alliance. This portrait is one in a series of portraits that feature “people of Medicine by Design.” Some minor edits may have been made to the original published version. Jacqueline Getfield, PhD, project...

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“Regenerative medicine news under the microscope” is a monthly feature highlighting a selection of impactful research findings and headlines across the many subfields of regenerative medicine. Fall is finally here! September really delivered – lots of interesting research to cover. In this edition, I discuss intestinal organoids re-imagined as a cell therapy, lab-created blood stem...

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Phil Vanek is responsible for technical due diligence and evaluation of potential investments, as well as guiding operational, R&D and strategic initiatives carried out at portfolio companies. An entrepreneurial and strategic international business leader, Phil joins Gamma Biosciences from GE Healthcare’s Cell and Gene Therapy business unit where he directed strategy and portfolio growth. Phil received his Ph.D. in Biochemistry and Molecular Biology at Georgetown University Medical Center followed by an IRTA fellowship at the National Cancer…

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